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Synaptotagmin-7 Monoclonal Antibody (N275/14)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
75-265
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
N275/14
Immunogen
Fusion protein amino acids 150-239 (cytoplasmic C2A domain) of mouse Synaptotagmin-7 (accession number Q9R0N7) produced recombinantly in E. Coli.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4
Contains
0.065% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alternatively spliced; long form; protein Syt7; short form; synaptotagmin VII; SYT-7; sytVII; truncated form 1; truncated form 2; unnamed protein product
Gene Aliases: B230112P13Rik; SytVII
UniProt ID: (Mouse) Q9R0N7, (Rat) Q62747
Entrez Gene ID: (Mouse) 54525, (Rat) 59267
plasma membrane repair
vesicle fusion
phagocytosis
regulation of dopamine secretion
vesicle-mediated transport
calcium ion regulated exocytosis
regulation of calcium ion-dependent exocytosis
insulin secretion
regulation of endocytosis
synaptic vesicle recycling
positive regulation of calcium ion-dependent exocytosis
regulation of bone remodeling
calcium ion-regulated exocytosis of neurotransmitter
regulation of phagocytosis
regulation of insulin secretion
positive regulation of transport
regulation of glucagon secretion
vesicle-mediated cholesterol transport
phagosome-lysosome fusion
calcium-dependent activation of synaptic vesicle fusion
regulation of synaptic vesicle endocytosis
short-term synaptic potentiation
calcium ion regulated lysosome exocytosis
detection of calcium ion
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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