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NSD3 Monoclonal Antibody (N348/82)
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Product Details
75-322
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
N348/82
Immunogen
Fusion protein amino acids 21-251 (N-terminus) of human NSD3 (accession number Q9BZ95) produced recombinantly in E. Coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4
Contains
0.065% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Target Information
This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. The function of the protein has not been determined. Two alternatively spliced variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp667H044; FLJ20353; Histone-lysine N-methyltransferase NSD3; MGC126766; MGC142029; Nuclear SET domain-containing protein 3; Protein whistle; unnamed protein product; WHSC1-like 1 isoform 9 with methyltransferase activity to lysine; WHSC1-like protein 1; Wolf-Hirschhorn syndrome candidate 1-like 1; Wolf-Hirschhorn syndrome candidate 1-like protein 1; Wolf-Hirschhorn syndrome candidate 1-like protein 1 homolog
Gene Aliases: 6720429E03; A530023P05; AI528490; DC28; KMT3F; KMT3G; NSD3; pp14328; WHISTLE; WHSC1L1
UniProt ID: (Human) Q9BZ95, (Mouse) Q6P2L6
Entrez Gene ID: (Human) 54904, (Rat) 290831, (Mouse) 234135
protein binding
methyltransferase activity
zinc ion binding
transferase activity
histone methyltransferase activity
histone methyltransferase activity (H3-K4 specific)
metal ion binding
histone methyltransferase activity (H3-K36 specific)
histone methyltransferase activity (H3-K27 specific)
transcription regulator activator activity
histone H3 methyltransferase activity
histone H3K4 dimethyltransferase activity
histone H3K27 trimethyltransferase activity
histone H3K27 dimethyltransferase activity
molecular_function
histone-lysine N-methyltransferase activity
biological_process
histone methylation
peptidyl-lysine methylation
negative regulation of transcription, DNA-templated
histone H3-K4 methylation
histone H3-K27 methylation
chromatin organization
chromatin remodeling
regulation of transcription, DNA-templated
methylation
positive regulation of transcription, DNA-templated
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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