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ANO6/TMEM16F Monoclonal Antibody (N429/19)

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ANO6/TMEM16F Monoclonal Antibody (N429/19)

Product Details

75-418

Applications
Tested Dilution
Publications

Western Blot (WB)

Assay-dependent
-

Immunohistochemistry (Frozen) (IHC (F))

Assay-dependent
-

Immunocytochemistry (ICC/IF)

Assay-dependent
-

ELISA (ELISA)

Assay-dependent
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

N429/19

Immunogen

Fusion protein amino acids 1-294 (cytoplasmic N-terminus) of human ANO6 (accession number Q4KMQ2) produced recombinantly in E. Coli.
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Amount

100 µg

Purification

Protein A

Storage buffer

TBS, pH 7.4

Contains

0.065% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Dry ice (international)

Product Specific Information

For maximum recovery of product, centrifuge the vial prior to removing the cap.

Target Information

May act as a calcium-activated chloride channel.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Anoctamin-6; SCAN channel; Small-conductance calcium-activated nonselective cation channel; Transmembrane protein 16F; unnamed protein product

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Gene Aliases: 2900059G15Rik; AA407480; ANO6; AW554778; BDPLT7; F730003B03Rik; SCTS; TMEM16F

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UniProt ID: (Human) Q4KMQ2, (Mouse) Q6P9J9

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Entrez Gene ID: (Human) 196527, (Rat) 315272, (Mouse) 105722

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Function(s)
calcium activated cation channel activity intracellular calcium activated chloride channel activity voltage-gated ion channel activity voltage-gated chloride channel activity chloride channel activity protein binding phospholipid scramblase activity metal ion binding protein dimerization activity molecular_function protein homodimerization activity
Process(es)
activation of blood coagulation via clotting cascade ion transport chloride transport lipid transport blood coagulation phospholipid scrambling positive regulation of bone mineralization bleb assembly ion transmembrane transport positive regulation of ion transmembrane transport purinergic nucleotide receptor signaling pathway sodium ion transmembrane transport positive regulation of apoptotic process negative regulation of cell volume pore complex assembly positive regulation of phagocytosis, engulfment calcium activated phosphatidylserine scrambling calcium activated phosphatidylcholine scrambling calcium ion transmembrane transport positive regulation of monocyte chemotaxis phosphatidylserine exposure on blood platelet chloride transmembrane transport positive regulation of potassium ion export across plasma membrane positive regulation of endothelial cell apoptotic process dendritic cell chemotaxis cation transport phospholipid transport bone mineralization involved in bone maturation regulation of anion transport calcium activated phospholipid scrambling calcium activated galactosylceramide scrambling phosphatidylserine exposure on apoptotic cell surface cation transmembrane transport positive regulation of potassium ion export transport regulation of ion transmembrane transport regulation of anion transmembrane transport
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