Product References
Influenza A virus reassortment in mammals gives rise to genetically distinct within-host subpopulations.
Nature communications
Ganti K,Bagga A,Carnaccini S,Ferreri LM,Geiger G,Joaquin Caceres C,Seibert B,Li Y,Wang L,Kwon T,Li Y,Morozov I,Ma W,Richt JA,Perez DR,Koelle K,Lowen AC
A-21287 was used in Immunohistochemistry, Immunocytochemistry, Western Blot to indicate that the dynamics of viral replication in mammals allow diversification through reassortment but that the spatial compartmentalization of variants likely shapes their evolution and onward transmission.
Fri Nov 11 00:00:00 EST 2022
Function-based high-throughput screening for antibody antagonists and agonists against G protein-coupled receptors.
Communications biology
Ren H,Li J,Zhang N,Hu LA,Ma Y,Tagari P,Xu J,Zhang MY
Published figure using HA Tag monoclonal antibody (Product # A-21287) in Flow Cytometry
Thu Mar 26 00:00:00 EDT 2020
A toolbox of nanobodies developed and validated for use as intrabodies and nanoscale immunolabels in mammalian brain neurons.
eLife
Dong JX,Lee Y,Kirmiz M,Palacio S,Dumitras C,Moreno CM,Sando R,Santana LF,Südhof TC,Gong B,Murray KD,Trimmer JS
A-21287 was used in Immunohistochemistry to report the generation and validation of nAbs against a set of proteins prominently expressed at specific subcellular sites in mammalian brain neurons.
Mon Sep 30 00:00:00 EDT 2019
Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch.
Cell
Liu N,Hargreaves VV,Zhu Q,Kurland JV,Hong J,Kim W,Sher F,Macias-Trevino C,Rogers JM,Kurita R,Nakamura Y,Yuan GC,Bauer DE,Xu J,Bulyk ML,Orkin SH
A-21287 was used in Antibody array to establish a requirement for a zinc-finger cluster in BCL11A in repression and identify a preferred DNA recognition sequence.
Thu Apr 05 00:00:00 EDT 2018
Host Nitric Oxide Disrupts Microbial Cell-to-Cell Communication to Inhibit Staphylococcal Virulence.
Cell host & microbe
Urbano R,Karlinsey JE,Libby SJ,Doulias PT,Ischiropoulos H,Warheit-Niemi HI,Liggitt DH,Horswill AR,Fang FC
A-21287 was used in Western blotting following immunoprecipitation to demonstrate an anti-virulence mechanism for nitric oxide in innate immunity.
Wed May 09 00:00:00 EDT 2018
Host Nitric Oxide Disrupts Microbial Cell-to-Cell Communication to Inhibit Staphylococcal Virulence.
Cell host & microbe
Urbano R,Karlinsey JE,Libby SJ,Doulias PT,Ischiropoulos H,Warheit-Niemi HI,Liggitt DH,Horswill AR,Fang FC
A-21287 was used in Western blotting following immunoprecipitation to demonstrate an anti-virulence mechanism for nitric oxide in innate immunity.
Wed May 09 00:00:00 EDT 2018
Duplicated TLR5 of zebrafish functions as a heterodimeric receptor.
Proceedings of the National Academy of Sciences of the United States of America
Voogdt CGP,Wagenaar JA,van Putten JPM
A-21287 was used in Immunocytochemistry-immunoflourescence to study the coevolution of duplicated toll-like receptor 5 in zebrafish.
Tue Apr 03 00:00:00 EDT 2018
Evolutionary Regression and Species-Specific Codon Usage of TLR15.
Frontiers in immunology
Voogdt CGP,Merchant ME,Wagenaar JA,van Putten JPM
A-21287 was used in Immunocytochemistry to investigate the functional evolution of Toll-like receptor 15.
Thu Oct 03 00:00:00 EDT 2019
Onsite GTP fuelling via DYNAMO1 drives division of mitochondria and peroxisomes.
Nature communications
Imoto Y,Abe Y,Honsho M,Okumoto K,Ohnuma M,Kuroiwa H,Kuroiwa T,Fujiki Y
A-21287 was used in Western Blotting to study the role of dynamin-based ring motive-force organiser 1 in mitochondrial division and peroxisome-dividing machinery.
Tue Nov 06 00:00:00 EST 2018
Differential phosphorylation signals control endocytosis of GPR15.
Molecular biology of the cell
Okamoto Y,Shikano S
A-21287 was used in Western Blot to demonstrate that phosphorylation signals may differentially control cell surface density of GPR15 through endocytosis.
Tue Aug 15 00:00:00 EDT 2017
Bacterial flagella grow through an injection-diffusion mechanism.
eLife
Renault TT,Abraham AO,Bergmiller T,Paradis G,Rainville S,Charpentier E,Guet CC,Tu Y,Namba K,Keener JP,Minamino T,Erhardt M
A21287 was used in immunocytochemistry to see that bacterial flagella growth outside the cell involves simple, injection-diffusion mechanism controls
Mon Mar 06 00:00:00 EST 2017
Crystal Structure of the Human Cannabinoid Receptor CB1.
Cell
Hua T,Vemuri K,Pu M,Qu L,Han GW,Wu Y,Zhao S,Shui W,Li S,Korde A,Laprairie RB,Stahl EL,Ho JH,Zvonok N,Zhou H,Kufareva I,Wu B,Zhao Q,Hanson MA,Bohn LM,Makriyannis A,Stevens RC,Liu ZJ
A21287 was used in immunocytochemistry to report the crystal structure of human CB1 in complex with AM6538
Thu Oct 20 00:00:00 EDT 2016
Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism.
Nature structural & molecular biology
Lu A,Li Y,Schmidt FI,Yin Q,Chen S,Fu TM,Tong AB,Ploegh HL,Mao Y,Wu H
A-21287 was used in Immunocytochemistry to investigate the biophysical properties of two caspase-1-like CARD-only proteins: human inhibitor of CARD and ICEBERG.
Sun May 01 00:00:00 EDT 2016
EGFR-targeted mAb therapy modulates autophagy in head and neck squamous cell carcinoma through NLRX1-TUFM protein complex.
Oncogene
Lei Y,Kansy BA,Li J,Cong L,Liu Y,Trivedi S,Wen H,Ting JP,Ouyang H,Ferris RL
A-21287 was used in ICC/IF to identify a novel signalling hub centring on the NLRX1 (nucleotide-binding, lots of leucine-rich repeats-containing protein member X1)-TUFM (Tu translation elongation factor mitochondrial) protein complex, promoting autophagic flux.
Thu Sep 08 00:00:00 EDT 2016
ATG16L1 phosphorylation is oppositely regulated by CSNK2/casein kinase 2 and PPP1/protein phosphatase 1 which determines the fate of cardiomyocytes during hypoxia/reoxygenation.
Autophagy
Song H,Pu J,Wang L,Wu L,Xiao J,Liu Q,Chen J,Zhang M,Liu Y,Ni M,Mo J,Zheng Y,Wan D,Cai X,Cao Y,Xiao W,Ye L,Tu E,Lin Z,Wen J,Lu X,He J,Peng Y,Su J,Zhang H,Zhao Y,Lin M,Zhang Z
A-21287 was used in immunoprecipitation to investigate the regulatory mechanism and role of ATG16L1 phosphorylation in autophagy induction using cardiomyocytes.
Mon Jun 20 00:00:00 EDT 2016
The protein synthesis inhibitor blasticidin s enters mammalian cells via leucine-rich repeat-containing protein 8D.
The Journal of biological chemistry
Lee CC,Freinkman E,Sabatini DM,Ploegh HL
Published figure using HA Tag monoclonal antibody (Product # A-21287) in Immunocytochemistry
Fri Jun 13 00:00:00 EDT 2014
The protein synthesis inhibitor blasticidin s enters mammalian cells via leucine-rich repeat-containing protein 8D.
The Journal of biological chemistry
Lee CC,Freinkman E,Sabatini DM,Ploegh HL
Published figure using HA Tag monoclonal antibody (Product # A-21287) in Immunocytochemistry
Fri Jun 13 00:00:00 EDT 2014
Biased suppression of TP homodimerization and signaling through disruption of a TM GxxxGxxxL helical interaction motif.
Journal of lipid research
Frey AJ,Ibrahim S,Gleim S,Hwa J,Smyth EM
A-21287 was used in Flow cytometry/Cell sorting to elucidate the biased suppression of TXA2 receptor homodimerisation and signalling through disruption of a transmembrane GxxxGxxxL helical interaction motif.
Sat Jun 01 00:00:00 EDT 2013
Kinetics of 5-HT2B receptor signaling: profound agonist-dependent effects on signaling onset and duration.
The Journal of pharmacology and experimental therapeutics
Unett DJ,Gatlin J,Anthony TL,Buzard DJ,Chang S,Chen C,Chen X,Dang HT,Frazer J,Le MK,Sadeque AJ,Xing C,Gaidarov I
A-21287 was used in immunocytochemistry to elucidate ergot signaling.
Sun Dec 01 00:00:00 EST 2013
Novel compound heterozygous mutations of the growth hormone-releasing hormone receptor gene in a case of isolated growth hormone deficiency.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society
Soneda A,Adachi M,Muroya K,Asakura Y,Takagi M,Hasegawa T,Inoue H,Itakura M
A-21287 was used in immunocytochemistry to elucidate the pathogenesis of isolated growth hormone deficiency in a Japanese girl without consanguinity.
Thu Aug 01 00:00:00 EDT 2013
In vitro affinity screening of protein and peptide binders by megavalent bead surface display.
Protein engineering, design & selection : PEDS
Diamante L,Gatti-Lafranconi P,Schaerli Y,Hollfelder F
A-21287 was used in flow cytometry to develop and characterize an in vitro bead surface display system
Tue Oct 01 00:00:00 EDT 2013
The cyclin A centrosomal localization sequence recruits MCM5 and Orc1 to regulate centrosome reduplication.
Journal of cell science
Ferguson RL,Pascreau G,Maller JL
A-21287 was used in immunocytochemistry to report that cyclin A interacts with both MCM5 and Orc1 in a centrosomal localization sequence-dependent but Cdk-independent manner
Sun Aug 15 00:00:00 EDT 2010
Feed-forward regulation of a cell fate determinant by an RNA-binding protein generates asymmetry in yeast.
Genetics
Wolf JJ,Dowell RD,Mahony S,Rabani M,Gifford DK,Fink GR
A-21287 was used in flow cytometry to investigate how FLO11 contributes to filamentous growth of yeast
Tue Jun 01 00:00:00 EDT 2010
The SUMO-targeted ubiquitin ligase subunit Slx5 resides in nuclear foci and at sites of DNA breaks.
Cell cycle (Georgetown, Tex.)
Cook CE,Hochstrasser M,Kerscher O
A-21287 was used in Immunocytochemistry-immunoflourescence to investigate the subnuclear localisation and potential chromatin association of the SUMO-targeted ubiquitin ligase subunit, Slx5.
Wed Apr 01 00:00:00 EDT 2009
N-linked glycosylation and its impact on the electrophoretic mobility and function of the human proton-coupled folate transporter (HsPCFT).
Biochimica et biophysica acta
Unal ES,Zhao R,Qiu A,Goldman ID
A-21287 was used in immunocytochemistry to investigate the human proton-coupled folate transporter
Sun Jun 01 00:00:00 EDT 2008
An ectromelia virus profilin homolog interacts with cellular tropomyosin and viral A-type inclusion protein.
Virology journal
Butler-Cole C,Wagner MJ,Da Silva M,Brown GD,Burke RD,Upton C
A-21287 was used in immunocytochemistry and western blot identify cellular and viral proteins that interact with a poxviral profilin homolog
Tue Jul 24 00:00:00 EDT 2007
Nicotinic acid receptor agonists differentially activate downstream effectors.
The Journal of biological chemistry
Richman JG,Kanemitsu-Parks M,Gaidarov I,Cameron JS,Griffin P,Zheng H,Guerra NC,Cham L,Maciejewski-Lenoir D,Behan DP,Boatman D,Chen R,Skinner P,Ornelas P,Waters MG,Wright SD,Semple G,Connolly DT
A-21287 was used in immunohistochemistry to study the signaling pathways induced by GPR109A pyrazole agonists that inhibit lipolysis but fail to elicit a flushing response
Fri Jun 22 00:00:00 EDT 2007
Tracking of quantum dot-labeled CFTR shows near immobilization by C-terminal PDZ interactions.
Molecular biology of the cell
Haggie PM,Kim JK,Lukacs GL,Verkman AS
A-21287 was used in immunocytochemistry to identify novel interactions of the cystic fibrosis transmembrane conductance regulator in living cells
Fri Dec 01 00:00:00 EST 2006
Visualization of integral and peripheral cell surface proteins in live Caenorhabditis elegans.
Journal of neuroscience methods
Gottschalk A,Schafer WR
A-21287 was used in immunocytochemistry to develop a method that allows for the fluorescent labeling of cell surface proteins in live Caenorhabditis elegans
Fri Jun 30 00:00:00 EDT 2006
A role for ADP-ribosylation factor 6 in the processing of G-protein-coupled receptors.
The Journal of biological chemistry
Madziva MT,Birnbaumer M
A-21287 was used in flow cytometry and immunocytochemistry to elucidate processing of G-protein-coupled receptors and a role for ADP-ribosylation factor 6
Fri Apr 28 00:00:00 EDT 2006
Amino acid changes in Drosophila alphaPS2betaPS integrins that affect ligand affinity.
The Journal of biological chemistry
Bunch TA,Helsten TL,Kendall TL,Shirahatti N,Mahadevan D,Shattil SJ,Brower DL
A-21287 was used in flow cytometry develop and characterize methods to study integrin affinity modulation
Fri Feb 24 00:00:00 EST 2006
Identification and characterization of novel nicotinic receptor-associated proteins in Caenorhabditis elegans.
The EMBO journal
Gottschalk A,Almedom RB,Schedletzky T,Anderson SD,Yates JR,Schafer WR
A-21287 was used in immunohistochemistry to identify nicotinic acetylcholine receptor accessory proteins
Wed Jul 20 00:00:00 EDT 2005
The divergent DSL ligand Dll3 does not activate Notch signaling but cell autonomously attenuates signaling induced by other DSL ligands.
The Journal of cell biology
Ladi E,Nichols JT,Ge W,Miyamoto A,Yao C,Yang LT,Boulter J,Sun YE,Kintner C,Weinmaster G
A-21287 was used in flow cytometry to study Dll3-mediated signaling
Mon Sep 12 00:00:00 EDT 2005
Separation of the Saccharomyces cerevisiae Paf1 complex from RNA polymerase II results in changes in its subnuclear localization.
Eukaryotic cell
Porter SE,Penheiter KL,Jaehning JA
A-21287 was used in immunocytochemistry to elucidate the fate of the Paf1C when dissociated from Pol II
Sat Jan 01 00:00:00 EST 2005
