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Invitrogen
CD79a Monoclonal Antibody (HM47), Alexa Fluor™ 647
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FIGURE: 1 / 3
CD79a Antibody (A51006) in IHC (P)
Immunohistochemical analysis of CD79a was performed using formalin-fixed paraffin-embedded human tonsil tissue sections. To expose the target protein, heat-induced epitope retrieval was performed on de-paraffinized sections using eBioscience™ IHC Antigen Retrieval Solution - High pH (10X) (Product # 00-4956-58) diluted to 1X solution in water in a decloaking chamber at 110 degree Celsius for 15 minutes. Fol... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
A51006
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
HM47
Immunogen
Synthetic peptide corresponding to C terminal amino acids 208-222 of human CD79a
Conjugate
Alexa Fluor™ 647
Alexa Fluor™ 647
Alexa Fluor™ 647
Excitation/Emission Max
650/671 nm
View spectra
Form
Liquid
Concentration
0.05 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.0325% sodium azide
Storage conditions
4°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
CD79a is a disulphide-linked heterodimer that includes B29 (CD79b) polypeptide. CD79a is a B lymphocyte antigen receptor with an antigen-specific surface component Ig (immunoglobulin) that associates with Ig-alpha and Ig-beta, necessary elements for the expression and function of the B-cell antigen receptor. CD79a first appears at pre-B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD79; CD79a antigen (immunoglobulin-associated alpha); CD79a molecule, immunoglobulin-associated alpha; extracellular domain; ig-alpha; MB-1 membrane glycoprotein; membrane-bound immunoglobulin associated protein; membrane-bound immunoglobulin-associated protein; signal transduction via sig in B lymphocytes; putative; similar to Homo sapiens CD79A antigen (immunoglobulin-associated alpha) encoded by GenBank Accession Number U05259; surface IgM-associated protein; unnamed protein product
Gene Aliases: IGA; IGAlpha; MB-1; MB1
UniProt ID: (Human) P11912
Entrez Gene ID: (Human) 973
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