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Agrisera
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Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Arabidopsis thaliana
ABA2 encodes a cytosolic short-chain dehydrogenase/reductase that catalyzes the NAD-dependent conversion of xanthoxin to abscisic aldehyde, a key late step in the primary abscisic acid (ABA) biosynthetic pathway derived from carotenoids. Positioned downstream of NCED-mediated 9-cis-epoxycarotenoid cleavage and upstream of AAO3 (abscisic aldehyde oxidase), ABA2 is rate-influential for ABA accumulation in response to drought, salinity, and developmental cues such as seed maturation. Loss-of-function mutations in ABA2 reduce ABA levels, leading to impaired stomatal closure, enhanced transpirational water loss, reduced seed dormancy and desiccation tolerance, and altered stress-responsive gene expression; conversely, overexpression can elevate ABA content and stress resilience. ABA2 is broadly expressed with enrichment in vascular and guard cell-associated tissues and is transcriptionally and post-transcriptionally regulated by environmental signals and metabolic status. As a central node linking carotenoid metabolism to ABA signaling outputs, ABA2 impacts plant water-use efficiency, growth-stress tradeoffs, and seed physiology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ABA DEFICIENT 2; ARABIDOPSIS THALIANA ABA DEFICIENT 2; AT1G52340; ATABA2; ATSDR1; F19K6.3; F19K6_3; GIN1; GLUCOSE INSENSITIVE 1; IMPAIRED SUCROSE INDUCTION 4; ISI4; SALT RESISTANT 1; SDR1; SHORT-CHAIN DEHYDROGENASE REDUCTASE 1; SHORT-CHAIN DEHYDROGENASE/REDUCTASE 1; SIS4; SRE1; SUGAR-INSENSITIVE 4
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