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Invitrogen
ABCA12 Polyclonal Antibody
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Product Details
PA5-122303
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant ABCA12 (Val1346~Thr1577) with two N-terminal Tags, His-tag and T7-tag expressed in E.coli.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ABCA12; ATP-binding cassette 12; ATP-binding cassette sub-family A member 12; ATP-binding cassette transporter 12; ATP-binding cassette, sub-family A (ABC1), member 12; DKFZp434G232; FLJ41584; Glucosylceramide transporter ABCA12; unnamed protein product
Gene Aliases: ABC12; ABCA12; ARCI4A; ARCI4B; ICR2B; LI2
UniProt ID: (Human) Q86UK0
Entrez Gene ID: (Human) 26154
nucleotide binding
receptor binding
lipid transporter activity
protein binding
ATP binding
ATPase activity
lipid-transporting ATPase activity
apolipoprotein A-I receptor binding
ATPase activity, coupled to transmembrane movement of substances
ATPase-coupled intramembrane lipid transporter activity
ABC-type transporter activity
corneocyte desquamation
ceramide metabolic process
lipid transport
intracellular protein transport
positive regulation of cholesterol efflux
cellular homeostasis
keratinocyte differentiation
keratinization
positive regulation of cholesterol transport
positive regulation of intracellular lipid transport
secretion by cell
cholesterol efflux
phospholipid efflux
lipid translocation
ceramide transport
surfactant homeostasis
skin morphogenesis
regulated exocytosis
regulation of keratinocyte differentiation
lung alveolus development
establishment of localization in cell
transmembrane transport
lipid homeostasis
regulation of insulin secretion involved in cellular response to glucose stimulus
establishment of skin barrier
protein localization to plasma membrane
positive regulation of protein localization to cell surface
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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