Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | View 2 publications 2 publications |
Immunohistochemistry (IHC) |
- | View 1 publication 1 publication |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:20-1:200 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Published species |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
ABCB6 Fusion Protein Ag0461 (57-267 aa encoded by BC000559) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.2 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: AGADSLSWG AGPRISPYVL QLLLATLQAA LPLAGLAGRV GTARGAPLPS YLLLASVLES LAGACGLWLL VVERSQARQR LAMGIWIKFR HSPGLLLLWT VAFAAENLAL VSWNSPQWWW ARADLGQQVQ FSLWVLRYVV SGGLFVLGLW APGLRPQSYT LQVHEEDQDV ERSQVRSAAQ QSTWRDFGRK LRLLSGYLWP RGSPALQLVV LI (57-267 aa encoded by BC000559)
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies. This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP-binding cassette half-transporter; ATP-binding cassette sub-family B member 6, mitochondrial; ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group); EST45597; FLJ22414; Mitochondrial ABC transporter 3; Mt-ABC transporter 3; P-glycoprotein-related protein; Ubiquitously-expressed mammalian ABC half transporter
Gene Aliases: ABC; ABC14; ABCB6; DUH3; LAN; MCOPCB7; MTABC3; PRP; PSHK2; UMAT
UniProt ID: (Human) Q9NP58
Entrez Gene ID: (Human) 10058
Molecular Function:
ATP-binding cassette (ABC) transporter
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