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Proteintech
ABCD1 Polyclonal Antibody
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Product Details
18138-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ABCD1 Fusion Protein Ag12757 (358-745 aa encoded by BC025358)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Amount
34.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SESDAEAVK KAALEKKEEE LVSERTEAFT IARNLLTAAA DAIERIMSSY KEVTELAGYT ARVHEMFQVF EDVQRCHFKR PRELEDAQAG SGTIGRSGVR VEGPLKIRGQ VVDVEQGIIC ENIPIVTPSG EVVVASLNIR VEEGMHLLIT GPNGCGKSSL FRILGGLWPT YGGVLYKPPP QRMFYIPQRP YMSVGSLRDQ VIYPDSVEDM QRKGYSEQDL EAILDVVHLH HILQREGGWE AMCDWKDVLS GGEKQRIGMA RMFYHRPKYA LLDECTSAVS IDVEGKIFQA AKDAGIALLS ITHRPSLWKY HTHLLQFDGE GGWKFEKLDS AARLSLTEEK QRLEQQLAGI PKMQRRLQEL CQILGEAVAP AHVPAPSPQG PGGLQGAST (358-745 aa encoded by BC025358)
Target Information
This gene is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein originates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Adrenoleukodystrophy protein; ALDP; ATP-binding cassette sub-family D member 1; ATP-binding cassette, sub-family D (ALD), member 1
Gene Aliases: ABC42; ABCD1; ALD; ALDP; AMN
UniProt ID: (Human) P33897
Entrez Gene ID: (Human) 215
nucleotide binding
long-chain fatty acid transporter activity
protein binding
ATP binding
organophosphate ester transmembrane transporter activity
ABC-type fatty-acyl-CoA transporter activity
nucleobase-containing compound transmembrane transporter activity
hydrolase activity
ATPase activity
enzyme binding
ATPase activity, coupled to transmembrane movement of substances
identical protein binding
protein homodimerization activity
amide transmembrane transporter activity
ADP binding
acyl-CoA hydrolase activity
very long chain acyl-CoA hydrolase activity
ABC-type transporter activity
sulfur compound transmembrane transporter activity
very long-chain fatty acid metabolic process
regulation of oxidative phosphorylation
fatty acid biosynthetic process
fatty acid beta-oxidation
unsaturated fatty acid biosynthetic process
peroxisome organization
organophosphate ester transport
peroxisomal long-chain fatty acid import
fatty-acyl-CoA transport
peroxisomal membrane transport
nucleobase-containing compound transport
regulation of fatty acid metabolic process
fatty acid elongation
regulation of fatty acid beta-oxidation
positive regulation of fatty acid beta-oxidation
alpha-linolenic acid metabolic process
very long-chain fatty-acyl-CoA catabolic process
long-chain fatty acid catabolic process
long-chain fatty acid biosynthetic process
very long-chain fatty acid catabolic process
amide transport
myelin maintenance
linoleic acid metabolic process
regulation of mitochondrial depolarization
transmembrane transport
fatty acid homeostasis
sterol homeostasis
negative regulation of cytokine production involved in inflammatory response
regulation of cellular response to oxidative stress
fatty acid derivative biosynthetic process
negative regulation of reactive oxygen species biosynthetic process
neuron projection maintenance
positive regulation of unsaturated fatty acid biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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