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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the internal region of human ABHD12|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 150mM NaCl, 50% glycerol|
|Contains||0.02% sodium azide|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol , the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC , resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
2-arachidonoylglycerol hydrolase; ABHD12; ABHD12A; abhydrolase domain containing 12; abhydrolase domain-containing protein 12; BEM46L2; C20orf22; dJ965G21.2; DKFZP434P106; monoacylglycerol lipase ABHD12
1500011G07Rik; 6330583M11Rik; ABHD12; ABHD12A; AI431047; AW547313; BEM46L2; C20orf22; dJ965G21.2; PHARC