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Invitrogen
ACADL Polyclonal Antibody
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FIGURE: 1 / 4
ACADL Antibody (PA5-116549) in IHC (P)
Immunohistochemistry analysis of ACADL in paraffin-embedded human lung cancer. Samples were incubated with ACADL Polyclonal antibody (Product # PA5-116549) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-116549
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 31-210 of human ACADL (NP_0015991)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.2 mg/mL
Amount
120 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: SH-SY5Y, Mouse liver, Mouse kidney, Mouse heart, Rat spinal cord
Immunogen sequence: GGEERLETPS AKKLTDIGIR RIFSPEHDIF RKSVRKFFQE EVIPHHSEWE KAGEVSREVW EKAGKQGLLG VNIAEHLGGI GGDLYSAAIV WEEQAYSNCS GPGFSIHSGI VMSYITNHGS EEQIKHFIPQ MTAGKCIGAI AMTEPGAGSD LQGIKTNAKK DGSDWILNGS KVFISNGSLS
Target Information
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: acetyl-Coenzyme A dehydrogenase, long-chain; Acyl Coenzyme A dehydrogenase, long chain; acyl-Coenzyme A dehydrogenase, long chain; acyl-Coenzyme A dehydrogenase, long-chain; LCAD long chain acyl-CoA dehydrogenase; long chain acyl-CoA dehydrogenase precursor (EC 1.3.99.2); long-chain acyl-CoA dehydrogenase; medium-chain acyl-CoA dehydrogenase, mitochondrial; unnamed protein product
Gene Aliases: ACAD4; ACOADA; LCAD
UniProt ID: (Human) P28330, (Rat) P15650, (Mouse) P51174
Entrez Gene ID: (Human) 33, (Rat) 25287, (Mouse) 11363
acyl-CoA dehydrogenase activity
long-chain-acyl-CoA dehydrogenase activity
protein binding
oxidoreductase activity, acting on the CH-CH group of donors
very-long-chain-acyl-CoA dehydrogenase activity
protein homodimerization activity
flavin adenine dinucleotide binding
medium-chain-acyl-CoA dehydrogenase activity
temperature homeostasis
fatty acid catabolic process
response to cold
lipid catabolic process
carnitine metabolic process, CoA-linked
fatty acid beta-oxidation using acyl-CoA dehydrogenase
carnitine catabolic process
long-chain fatty acid catabolic process
negative regulation of fatty acid biosynthetic process
negative regulation of fatty acid oxidation
regulation of cholesterol metabolic process
positive regulation of cold-induced thermogenesis
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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