|Tested species reactivity||Human, Mouse|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 18 and 341 of Human ACADVL|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
PA5-29959 targets ACADVL in IF, IHC (P), and WB applications and shows reactivity with Human and mouse samples.
The PA5-29959 immunogen is recombinant fragment corresponding to a region within amino acids 18 and 341 of Human ACADVL.
The protein encoded by this gene is targeted to the inner mitochondrial membrane where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenase is specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Characterization of the mammalian family of DCN-type NEDD8 E3 ligases.
PA5-29959 was used in western blot to analyze the DCN-type NEDD8 E3 ligase mammalian family
|Keuss MJ,Thomas Y,Mcarthur R,Wood NT,Knebel A,Kurz T||Journal of cell science (129:1441)||2016|