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Proteintech
ACMSD Polyclonal Antibody
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Product Details
26834-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ACMSD fusion protein Ag25230
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: VSYPRRFVGL GTLPMQAPEL AVKEMERCVK ELGFPGVQIG THVNEWDLNA QELFPVYAAA ERLKCSLFVH PWDMQMDGRM AKYWLPWLVG MPAETTIAIC SMIMGGVFEK FPKLKVCFAH GGGAFPFTVG RISHGFSMRP DLCAQDNPMN PKKYLGSFYT DALVHDPLSL KLLTDVIGKD KVILGTDYPF PLGELEPGKL IESMEE
Target Information
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM, Oct 2004]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Picolinate carboxylase
Gene Aliases: ACMSD
UniProt ID: (Human) Q8TDX5, (Mouse) Q8R519
Entrez Gene ID: (Human) 130013, (Mouse) 266645
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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