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Product Details
H00055902-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ACSS2 (AAH98422.1, 1 a.a. approximately 606 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.44 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MKGATTNICY NVLDRNVHEK KLGDKVAFYW EGNEPGETTQ ITYHQLLVQV CQFSNVLRKQ GIQKGDRVAI YMPMIPELVV AMLACARIGA LHSIVFAGFS SESLCERILD SSCSLLITTD AFYRGEKLVN LKELADEALQ KCQEKGFPVR CCIVVKHLGR AELGMGDSTS QSPPIKRSCP DVQISWNQGI DLWWHELMQE AGDECEPEWC DAEDPLFILY TSGSTGKPKG VVHTVGGYML YVATTFKYVF DFHAEDVFWC TADIGWITGH SYVTYGPLAN GATSVLFEGI PTYPDVNRLW SIVDKYKVTK FYTAPTAIRL LMKFGDEPVT KHSRASLQVL GTVGEPINPE AWLWYHRVVG AQRCPIVDTF WQTETGGHML TPLPGATPMK PGSATFPFFG VAPAILNESG EELEGEAEGY LVFKQPWPGI MRTVYGNHER FETTYFKKFP GYYVTGDGCQ RDQDGYYWIT GRIDDMLNVS GHLLSTAEVE SALVEHEAVA EAAVVGHPHP VKGECLYCFV TLCDGHTFSP KLTEELKKQI REKIGPIATP DYIQNAPGLP KTRSGKIMRR VLRKIAQNDH DLGDMSTVAD PSVISHLFSH RCLTIQ
Target Information
This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AceCS1; acetate thiokinase; Acetate--CoA ligase; acetate-CoA ligase; Acetyl-CoA synthetase; Acetyl-CoA synthetase 1; acetyl-Coenzyme A synthetase 2 (ADP forming); Acetyl-coenzyme A synthetase, cytoplasmic; ACS; Acyl-activating enzyme; Acyl-CoA synthetase short-chain family member 2; cytoplasmic acetyl-coenzyme A synthetase; Propionate--CoA ligase
Gene Aliases: ACAS2; ACECS; ACS; ACSA; ACSS2; dJ1161H23.1
UniProt ID: (Human) Q9NR19
Entrez Gene ID: (Human) 55902
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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