Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX13796-PEP)..
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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