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Invitrogen
ADAM2 Polyclonal Antibody
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FIGURE: 1 / 1
ADAM2 Antibody (PA5-87699) in WB
Western blot analysis of ADAM2 in extracts of various cell lines. Samples were incubated with ADAM2 Polyclonal antibody (Product # PA5-87699) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Product Details
PA5-87699
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 476-686 of human ADAM2 (Q99965)
Conjugate
Form
Liquid
Concentration
1.12 mg/mL
Amount
112 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: HL-60, MCF7, Jurkat, Raji, Mouse testis, Rat testis; Cellular Location: Membrane, Single-pass type I membrane protein
Immunogen sequence: PCGLNQWICI DGVCMSGDKQ CTDTFGKEVE FGPSECYSHL NSKTDVSGNC GISDSGYTQC EADNLQCGKL ICKYVGKFLL QIPRATIIYA NISGHLCIAV EFASDHADSQ KMWIKDGTSC GSNKVCRNQR CVSSSYLGYD CTTDKCNDRG VCNNKKHCHC SASYLPPDCS VQSDLWPGGS IDSGNFPPVA IPARLPERRY IENIYHSKPM R
Target Information
ADAM2 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM2 is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: a disintegrin and metallopeptidase domain 2; a disintegrin and metalloprotease domain 2; a disintegrin and metalloprotease domain (ADAM) 2; A disintegrin and metalloprotease domain 2 (Fertilin beta); a disintegrin and metalloproteinase; ADAM; ADAM 2; ADAMs; Cancer/testis antigen 15; CT15; disintegrin; Disintegrin and metalloproteinase domain-containing protein 2; fertilin beta; Fertilin subunit beta; metalloendopeptidases; PH-30; PH30; PH30-beta; unnamed protein product
Gene Aliases: ADAM2; AI323749; CRYN1; CRYN2; CT15; FTNB; PH-30; PH-30b; PH30; PH30-beta
UniProt ID: (Human) Q99965, (Rat) Q63202, (Mouse) Q60718
Entrez Gene ID: (Human) 2515, (Rat) 56806, (Mouse) 11495
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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