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Invitrogen
ADAMTS1 Polyclonal Antibody
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FIGURE: 1 / 1
ADAMTS1 Antibody (PA5149947) in WB
Western blot analysis of ADAMTS1 in Lane 1: Mouse Lung lysate; Lane 2: 293T cell lysate; Lane 3: A549 cell lysate. Samples were incubated with ADAMTS1 Polyclonal (Product # PA5149947) antibody using a dilution of 0.4 µg/mL, followed by HRP-Linked Caprine Anti-Rabbit IgG (0.2 µg/mL).
Product Details
PA5149947
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 1 (ADAMTS1) (Asp476-Pro614)
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
ADAMTS-1 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 1; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1; ADAM; ADAM-TS 1; ADAM-TS1; ADAMs; ADAMTS-1; ADAMTS1; extracellular protein with metalloprotease and TSP domains; human metalloproteinase with thrombospondin type 1 motifs; metalloendopeptidases; metalloprotease and thrombospondin-1; METH-1; unnamed protein product
Gene Aliases: ADAM-TS1; ADAMTS; ADAMTS-1; ADAMTS1; C3-C5; KIAA1346; METH-1; METH1
UniProt ID: (Human) Q9UHI8, (Mouse) E9QMN9
Entrez Gene ID: (Human) 9510, (Mouse) 11504
ovulation from ovarian follicle
kidney development
proteolysis
integrin-mediated signaling pathway
negative regulation of cell proliferation
negative regulation of angiogenesis
extracellular matrix organization
heart trabecula formation
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of vascular smooth muscle cell proliferation
positive regulation of vascular associated smooth muscle cell migration
positive regulation of neuron projection development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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