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Invitrogen
ADAMTS2 Polyclonal Antibody
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FIGURE: 1 / 1
ADAMTS2 Antibody (PA5-87766) in WB
Western blot analysis of ADAMTS2 in extracts of various cell lines. Samples were incubated with ADAMTS2 Polyclonal antibody (Product # PA5-87766) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-87766
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein (or fragment)
Conjugate
Form
Liquid
Concentration
1.47 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: A-375, U-87MG, THP-1, Rat thymus, ; Cellular Location: extracellular matrix, extracellular space
Immunogen sequence: PRNISDPSKK SYVVQWLSRP DPDSPIRKIS SKGHCQGDKS IFCRMEVLSR YCSIPGYNKL CCKSCNLYNN LTNVEGRIEP PPGKHNDIDV FMPTLPVPTV AMEVRPSPST PLEVPLNASS TNATEDHPET NAVDEPYKIH GLEDEVQPPN LIPRRPSPYE KTRNQRIQEL IDEMRKKEML GKF
Target Information
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in two transcript variants. The short transcript encodes a protein which has no significant procollagen N-peptidase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 2; a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2; ADAM; ADAM-TS 2; ADAMs; metalloendopeptidases; PC I-NP; pNPI; Procollagen I N-proteinase; Procollagen I/II amino propeptide-processing enzyme; Procollagen N-endopeptidase
Gene Aliases: ADAM-TS2; ADAMTS-2; ADAMTS-3; ADAMTS2; NPI; PC I-NP; PCI-NP; PCINP; PCPNI; PNPI; RGD1565950
UniProt ID: (Human) O95450
Entrez Gene ID: (Human) 9509, (Rat) 287899
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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