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Invitrogen
ADAMTS3 Polyclonal Antibody
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Product Details
PA5-51299
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide of human ADAMTS3
Conjugate
Form
Liquid
Concentration
1.7 mg/mL
Amount
170 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total ADAMTS3 protein.
Target Information
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene is the major procollagen II N-propeptidase. A deficiency of this protein may be responsible for dermatosparaxis, a genetic defect of connective tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 3; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3; ADAM; ADAM-TS 3; ADAM-TS3; ADAMs; ADAMTS-3; ADAMTS3; KIAA0366; metalloendopeptidases; PC II-NP; Procollagen II amino propeptide-processing enzyme; Procollagen II N-proteinase; unnamed protein product; zinc metalloendopeptidase
Gene Aliases: ADAMTS-4; ADAMTS3; HKLLS3; KIAA0366
UniProt ID: (Human) O15072
Entrez Gene ID: (Human) 9508
in utero embryonic development
proteolysis
vascular endothelial growth factor production
protein processing
extracellular matrix organization
collagen fibril organization
collagen catabolic process
collagen biosynthetic process
fibril organization
positive regulation of vascular endothelial growth factor signaling pathway
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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