Keep as concentrated solution.
Positive Control: mouse brain.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a member of the ADAMTS protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 4 antibody; A disintegrin and metalloproteinase with thrombospondin motifs 4; A disintegrin and metalloproteinase with thrombospondin motifs 4 antibody; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4; ADAM metallopeptidase with thrombospondin type 1 motif; ADAM-TS 4; ADAM-TS 4 antibody; ADAM-TS4 antibody; ADAMTS-2 antibody; ADAMTS-4; ADAMTS-4 antibody; ADAMTS4 antibody; ADMP-1 antibody; Aggrecanase-1; aggrecanase-1 antibody; KIAA0688 antibody
Gene Aliases: 3830423K05; ADAM-TS4; ADAMTS-2; Adamts4; ADMP-1; mKIAA0688
UniProt ID: (Mouse) Q8BNJ2
Entrez Gene ID: (Mouse) 240913