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Proteintech
ADH1A Polyclonal Antibody
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Product Details
17998-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ADH1A fusion protein Ag12467
Conjugate
Form
Liquid
Concentration
350 µg/mL
Amount
52.5 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Sequence of this protein is as follows: MSTAGKVIKC KAAVLWELKK PFSIEEVEVA PPKAHEVRIK MVAVGICGTD DHVVSGTMVT PLPVILGHEA AGIVESVGEG VTTVKPGDKV IPLAIPQCGK CRICKNPESN YCLKNDVSNP QGTLQDGTSR FTCRRKPIHH FLGISTFSQY TVVDENAVAK IDAASPLEKV CLIGCGFSTG YGSAVNVAKV TPGSTCAVFG LGGVGLSAIM GCKAAGAARI IAVDINKDKF AKAKELGATE CINPQDYKKP IQEVLKEMTD GGVDFSFEVI GRLDTMMASL LCCHEACGTS VIVGVPPDSQ NLSMNPMLLL TGRTWKGAIL GGFKSKECVP KLVADFMAKK FSLDALITHV LPFEKINEGF DLLHSGKSIR TILMF
Target Information
This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. This gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADH, alpha subunit; ADH-A2; Alcohol dehydrogenase 1; alcohol dehydrogenase 1 (class I), alpha polypeptide; alcohol dehydrogenase 1 temporal, liver; alcohol dehydrogenase 1, complex; alcohol dehydrogenase 1, electrophoretic; Alcohol dehydrogenase 1A; alcohol dehydrogenase 3, electrophoretic; Alcohol dehydrogenase A subunit; alcohol dehydrogenase alpha subunit (EC 1.1.1.1); Alcohol dehydrogenase subunit alpha; aldehyde reductase; class I alcohol dehydrogenase; unnamed protein product
Gene Aliases: Adh; Adh-1; Adh-1-t; Adh-1e; Adh-1t; Adh-3e; ADH-AA; ADH1; Adh1-e; Adh1-t; ADH1A; Adh1c; Adh1tl; Adh3-e; AI194826
UniProt ID: (Human) P07327, (Mouse) P00329, (Rat) P06757
Entrez Gene ID: (Human) 124, (Mouse) 11522, (Rat) 24172
alcohol dehydrogenase (NAD) activity
retinol dehydrogenase activity
protein binding
zinc ion binding
oxidoreductase activity
metal ion binding
butanol dehydrogenase (NAD+) activity
drug binding
ethanol binding
protein homodimerization activity
NAD binding
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
alcohol metabolic process
retinol metabolic process
retinoic acid metabolic process
retinoid metabolic process
ethanol catabolic process
ethanol oxidation
response to retinoic acid
response to testosterone
acetaldehyde biosynthetic process
behavioral response to ethanol
response to steroid hormone
oxidation-reduction process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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