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Proteintech
AFG3L2 Polyclonal Antibody
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Product Details
14631-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AFG3L2 Fusion Protein Ag6209 (449-797 aa encoded by BC065016)
Conjugate
Form
Liquid
Concentration
0.36 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: ILAGTNRPD ILDPALLRPG RFDRQIFIGP PDIKGRASIF KVHLRPLKLD STLEKDKLAR KLASLTPGFS GADVANVCNE AALIAARHLS DSINQKHFEQ AIERVIGGLE KKTQVLQPEE KKTVAYHEAG HAVAGWYLEH ADPLLKVSII PRGKGLGYAQ YLPKEQYLYT KEQLLDRMCM TLGGRVSEEI FFGRITTGAQ DDLRKVTQSA YAQIVQFGMN EKVGQISFDL PRQGDMVLEK PYSEATARLI DDEVRILIND AYKRTVALLT EKKADVEKVA LLLLEKEVLD KNDMVELLGP RPFAEKSTYE EFVEGTGSLD EDTSLPEGLK DWNKEREKEK EEPPGEKVAN (449-797 aa encoded by BC065016)
Target Information
AFG3L2 is a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. AFG3L2 gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders. This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: AFG3 ATPase family gene 3-like 2; AFG3 ATPase family member 3-like 2; AFG3 like AAA ATPase 2; AFG3(ATPase family gene 3)-like 2; AFG3-like AAA ATPase 2; AFG3-like protein 2; ATPase family gene 3, yeast; FLJ25993; Mitochondrial inner membrane m-AAA protease component AFG3L2; Paraplegin-like protein
Gene Aliases: 2310036I02Rik; AFG3L2; AW260507; Emv66; par; SCA28; SPAX5
UniProt ID: (Human) Q9Y4W6, (Mouse) Q8JZQ2
Entrez Gene ID: (Human) 10939, (Mouse) 69597, (Rat) 307350
protein complex assembly
axonogenesis
neuromuscular junction development
mitochondrial fusion
nerve development
mitochondrial protein processing
regulation of multicellular organism growth
cristae formation
myelination
protein import into mitochondrial intermembrane space
muscle fiber development
righting reflex
proteolysis
mitochondrion organization
obsolete death
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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