Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: QDGRHYFSL TWTFQFPHNK DTCYFAHCYP YTYTNLQEYL SGINNDPVRS KFCKIRVLCH TLARNMVYIL TITTPLKNSD SRKRKAVILT ARVHPGETNS SWIMKGFLDY ILGNSSDAQL LRDTFVFKVV PMLNPDGVIV GNYRCSLAGR DLNRNYTSLL KESFPSVWYT RNMVHRLMEK REVILYCDLH GHSRKENIFM YGCDGSDRSK TLYLQQRIFP LMLSKNCPDK FSFSACKFNV QKSKEGTGRV VMWKMGIRNS FTMEATFCGS TLGNKRGTHF STKDLESMGY HFCDSLLDYC DPDRTKYYRC LKELEEMERH ITLEKVFEDS DTPVIDITLD VESRELTFLL R (272-621 aa encoded by BC030651)
Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP/GTP binding protein-like 3; ATP/GTP-binding protein-like 3; CBCP3; Cytosolic carboxypeptidase 3; Protein deglutamylase CCP3
Gene Aliases: 2900053G10Rik; 4930431N21Rik; 6530406M24Rik; AGBL3; CCP3; RGD1561995
UniProt ID: (Human) Q8NEM8, (Mouse) Q8CDP0
Entrez Gene ID: (Human) 340351, (Mouse) 76223, (Rat) 500076
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