Invitrogen

AGPS Polyclonal Antibody

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AGPS Antibody in Western Blot (WB) — Western blot analysis of Alkyl-DHAP synthase using A) 30 µg 293T whole cell lysate and B) 30 µg whole cell lysate of human AGPS-transfected 293T cells. Samples were loaded onto a 7.5% SDS-PAGE gel and probed with an Alkyl-DHAP synthase polyclonal antibody (Product # PA5-27401) at a dilution of 1:1000.

Product Details

Tested Applications

Dilution

Western Blot (WB)

1:500-1:3000

Product Specifications

Species Reactivity

Human

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fragment corresponding to a region within amino acids 370 and 658 of Human Alkyl-DHAP synthase

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7, with 20% glycerol

Contains

0.025% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

RRID

AB_2544877

Product Specific Information

The PA5-27401 immunogen is recombinant fragment corresponding to a region within amino acids 370 and 658 of Human Alkyl-DHAP synthase.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Target Information

This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: ADAP-S; ADAS; ADHAPS; ADPS; Aging-associated gene 5 protein; aging-associated protein 5; ALDHPSY; Alkyl-DHAP synthase; alkyldihydroxyacetonephosphate synthase; Alkyldihydroxyacetonephosphate synthase, peroxisomal; Alkylglycerone-phosphate synthase; peroxisomal

Gene Aliases: AAG5; ADAP-S; ADAS; ADHAPS; ADPS; AGPS; ALDHPSY; RCDP3

UniProt ID: (Human) O00116

Entrez Gene ID: (Human) 8540

Molecular Function: dehydrogenase oxidoreductase