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Proteintech
AHI1 Polyclonal Antibody
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Product Details
22045-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AHI1 Fusion Protein Ag16885 (1-350 aa encoded by BC094800)
Conjugate
Form
Liquid
Concentration
0.18 mg/mL
Amount
27 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MPTAESEAK VKTKVRFEEL LKTHSDLMRE KKKLKKKLVR SEENISPDTI RSNLHYMKET TSDDPDTIRS NLPHIKETTS DDVSAANTNN LKKSTRVTKN KLRNTQLATE NPNGDASVEE DKQGKPNKKV IKTVPQLTTQ DLKPETPENK VDSTHQKTHT KPQPGVDHQK SEKANEGREE TDLEEDEELM QAYQCHVTEE MAKEIKRKIR KKLKEQLTYF PSDTLFHDDK LSSEKRKKKK EVPVFSKAET STLTISGDTV EGEQKKESSV RSVSSDSHQD DEISSMEQST EDSMQDDTKP KPKKTKKKTK AVADNNEDVD GDGVHEITSR DSPVYPKCLL DDDLVLGVYI H (1-350 aa encoded by BC094800)
Target Information
This gene is apparently required for both cerebellar and cortical development in humans. This gene mutations cause specific forms of Joubert syndrome-related disorders. Joubert syndrome (JS) is a recessively inherited developmental brain disorder with several identified causative chromosomal loci. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: abelson helper integration site 1 protein; Abelson helper integration site 1 protein homolog; AHI-1; contatins SH3 and WD40 domains; Jouberin; RP1-32B1.2; unnamed protein product
Gene Aliases: 1700015F03Rik; AHI-1; AHI1; D10Bwg0629e; dJ71N10.1; JBTS3; ORF1
UniProt ID: (Human) Q8N157
Entrez Gene ID: (Human) 54806, (Mouse) 52906
morphogenesis of a polarized epithelium
heart looping
positive regulation of receptor internalization
vesicle targeting
transmembrane receptor protein tyrosine kinase signaling pathway
central nervous system development
positive regulation of gene expression
retina layer formation
vesicle-mediated transport
cell projection organization
positive regulation of polarized epithelial cell differentiation
hindbrain development
protein localization to organelle
cellular protein localization
cloaca development
photoreceptor cell outer segment organization
pronephric nephron tubule morphogenesis
cilium assembly
negative regulation of apoptotic process
positive regulation of transcription from RNA polymerase II promoter
regulation of behavior
retina development in camera-type eye
cilium morphogenesis
specification of axis polarity
otic vesicle development
protein localization
cell differentiation
motile cilium assembly
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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