Immunogen sequence: MAASCVLLH TGQKMPLIGL GTWKSEPGQV KAAVKYALSV GYRHIDCAAI YGNEPEIGEA LKEDVGPGKA VPREELFVTS KLWNTKHHPE DVEPALRKTL ADLQLEYLDL YLMHWPYAFE RGDNPFPKNA DGTICYDSTH YKETWKALEA LVAKGLVQAL GLSNFNSRQI DDILSVASVR PAVLQVECHP YLAQNELIAH CQARGLEVTA YSPLGSSDRA WRDPDEPVLL EEPVVLALAE KYGRSPAQIL LRWQVQRKVI CIPKSITPSR ILQNIKVFDF TFSPEEMKQL NALNKNWRYI VPMLTVDGKR VPRDAGHPLY PFNDPY (1-325 aa encoded by B C000670)
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member, also known as aldehyde reductase, is involved in the reduction of biogenic and xenobiotic aldehydes and is present in virtually every tissue. Multiple alternatively spliced transcript variants of this gene exist, all encoding the same protein.
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Protein Aliases: 3-DG-reducing enzyme; AKR1A1 protein; alcohol dehydrogenase; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Aldo-keto reductase family 1 member A1; aldo-keto reductase family 1, member A1 (aldehyde reductase); aldo-keto reductase family 1, member A4 (aldehyde reductase); dihydrodiol dehydrogenase 3; epididymis secretory protein Li 6; epididymis secretory sperm binding protein Li 165mP; Glucuronate reductase; Glucuronolactone reductase; HEL-S-165mP; MGC12529; MGC1380; OTTHUMP00000009240
Gene Aliases: 2610201A18Rik; AKR1A1; Akr1a4; ALDR1; ALR; ARM; DD3; HEL-S-6