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Invitrogen
AKT2 Polyclonal Antibody
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Product Details
PA5-81313
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to the C-terminus of the Mouse AKT2/PKB beta
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Mouse AKT2/PKB beta.
Target Information
AKT2 is a phosphoinositide-dependent serine/threonine protein kinase that is enriched in insulin responsive tissues and has been implicated in the metabolic actions of the hormone. Akt is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphatidylinositol 3-kinase (PI 3-kinase). Akt2 is amplified and overexpressed in some human cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PKB beta; Protein kinase Akt-2; Protein kinase B beta; protein kinase B, beta; RAC-beta serine/threonine protein kinase; RAC-beta serine/threonine-protein kinase; RAC-PK-beta
Gene Aliases: 2410016A19Rik; Akt2; AW554154; PKB; PKBbeta
UniProt ID: (Mouse) Q60823
Entrez Gene ID: (Mouse) 11652
nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
protein kinase C binding
protein binding
ATP binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
non-receptor serine/threonine protein kinase
protein modifying enzyme
positive regulation of protein phosphorylation
carbohydrate metabolic process
glycogen metabolic process
glycogen biosynthetic process
glucose metabolic process
regulation of translation
protein phosphorylation
transport
apoptotic process
multicellular organism development
insulin receptor signaling pathway
carbohydrate transport
positive regulation of signal transduction
positive regulation of gene expression
negative regulation of plasma membrane long-chain fatty acid transport
positive regulation of sodium ion transport
positive regulation of glucose metabolic process
phosphorylation
positive regulation of cell migration
positive regulation of vesicle fusion
positive regulation of fatty acid beta-oxidation
peripheral nervous system myelin maintenance
cellular response to insulin stimulus
negative regulation of RNA splicing
positive regulation of peptidyl-serine phosphorylation
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
protein kinase B signaling
positive regulation of nitric oxide biosynthetic process
positive regulation of glycogen biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
positive regulation of glucose import
positive regulation of positive chemotaxis
intracellular protein transmembrane transport
cellular response to organic cyclic compound
protein localization to plasma membrane
positive regulation of protein targeting to membrane
activation of GTPase activity
positive regulation of cell motility
positive regulation of glucose import in response to insulin stimulus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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