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NeoBiotechnologies
ALCAM (Activated Leukocyte Cell Adhesion Molecule)/CD166 Recombinant Mouse Monoclonal Antibody (rMOG/07)
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FIGURE: 1 / 3
ALCAM (Activated Leukocyte Cell Adhesion Molecule)/CD166 Antibody (214-MSM3-P1ABX) in IHC (P)
Formalin-fixed, paraffin-embedded human parathyroid gland stained with ALCAM/CD166 Recombinant Mouse Monoclonal Antibody (rMOG/07). Inset: PBS instead of primary antibody; secondary only negative control.
Product Details
214-MSM3-P1ABX
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
rMOG/07
Immunogen
Raised against a 200 amino acid portion of human CD166.
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product cellular localization: Cell membrane.
Positive control: Human tonsil, spleen, colon or parathyroid gland.
Tissue specificity: Detected on hematopoietic stem cells derived from umbilical cord blood (PubMed:24740813). Detected on lymph vessel endothelial cells, skin and tonsil (PubMed:23169771). Detected on peripheral blood monocytes (PubMed:15048703). Detected on monocyte-derived dendritic cells (at protein level) (PubMed:16352806). Detected at low levels in spleen, placenta, liver (PubMed:9502422). Expressed by activated T-cells, B-cells, monocytes and thymic epithelial cells (PubMed:7760007). Isoform 1 and isoform 3 are detected in vein and artery endothelial cells, astrocytes, keratinocytes and artery smooth muscle cells (PubMed:15496415). Expressed by neurons in the brain. Restricted expression in tumor cell lines. Detected in highly metastasizing melanoma cell lines (PubMed:9502422).
Target Information
This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activated leukocyte cell adhesion molecule; CD166; CD166 antigen; FLJ38514; MGC71733
Gene Aliases: ALCAM; CD166; MEMD
UniProt ID: (Human) Q13740
Entrez Gene ID: (Human) 214
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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