This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: AEGAQIWCGE GVDKLSLPAR NQAGYFMLPT VITDIKDESC CMTEEIFGPV TCVVPFDSEE EVIERANNVK YGLAATVWSS NVGRVHRVAK KLQSGLVW
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 89%.
This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2-aminomuconic semialdehyde dehydrogenase; Aldehyde dehydrogenase 12; aldehyde dehydrogenase 8 family, member A1; Aldehyde dehydrogenase family 8 member A1; aldehyde dehydrogenase family protein; ALDH12
Gene Aliases: ALDH12; ALDH8A1; DJ352A20.2
UniProt ID: (Human) Q9H2A2
Entrez Gene ID: (Human) 64577