Bioss

ALOX12/12 Lipoxygenase Polyclonal Antibody

View all (17) ALOX12 antibodies

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Questions & Answers

Product Details

Applications

Tested Dilution

Publications

Immunofluorescence (IF)

Assay-dependent

-

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

-

Western Blot (WB)

Assay-dependent

-

Product Specifications

Species

Human, Mouse, Rat

Expression System

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from human 12 Lipoxygenase.

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS with 50% glycerol, 1% BSA

Contains

0.09% sodium azide

Storage conditions

-20°C

Target Information

Oxygenase and 14,15-leukotriene A4 synthase activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 12(S)-lipoxygenase; 12LOX; 12S LOX; 12S-lipoxygenase; 12S-LOX; arachidonate 12-lipoxygenase; Arachidonate 12-lipoxygenase, 12S-type; Arachidonate 15-lipoxygenase,15S-type; Linoleate 13S-lipoxygenase; Lipoxin synthase 12-LO; P-12LO; platelet 12-LOX; platelet-type 12-lipoxygenase; Platelet-type lipoxygenase 12

Gene Aliases: 12-LO; 12-LOX; 12LO; 12S-LOX; 9930022G08Rik; ALOX12; Alox12p; LOG12; P-12LO

UniProt ID: (Human) P18054, (Mouse) P39655

Entrez Gene ID: (Human) 239, (Rat) 287454, (Mouse) 11684

Molecular Function: oxidoreductase oxygenase

movement of cell or subcellular component aging positive regulation of cell proliferation positive regulation of endothelial cell migration positive regulation of gene expression negative regulation of muscle cell apoptotic process arachidonic acid metabolic process lipoxygenase pathway fatty acid oxidation positive regulation of cell growth positive regulation of cell migration superoxide anion generation negative regulation of apoptotic process positive regulation of cysteine-type endopeptidase activity involved in apoptotic process linoleic acid metabolic process positive regulation of endothelial cell differentiation positive regulation of angiogenesis positive regulation of cell adhesion positive regulation of vasodilation positive regulation of smooth muscle cell proliferation hepoxilin metabolic process hepoxilin biosynthetic process positive regulation of mitochondrial depolarization establishment of skin barrier cellular response to lipid reactive oxygen species metabolic process negative regulation of platelet aggregation leukotriene A4 metabolic process lipoxin metabolic process lipoxin A4 biosynthetic process lipoxin B4 biosynthetic process positive regulation of cell death positive regulation of apoptotic process oxidation-reduction process lipid metabolic process fatty acid metabolic process

Process(es)

arachidonate 12-lipoxygenase activity iron ion binding protein binding linoleate 13S-lipoxygenase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen hepoxilin-epoxide hydrolase activity hepoxilin A3 synthase activity hydrolase activity juvenile hormone epoxide hydrolase activity oxidoreductase activity epoxide hydrolase B activity phenanthrene-9,10-epoxide hydrolase (9R,10R-forming) activity epoxide hydrolase A activity phenanthrene-3,4-epoxide hydrolase activity phenanthrene-1,2-epoxide hydrolase activity phenanthrene-9,10-epoxide hydrolase (9S,10S-forming) activity phenanthrene-epoxide hydrolase activity phenanthrene-9,10-epoxide hydrolase activity pyrene-4,5-epoxide hydrolase activity metal ion binding dioxygenase activity