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Product Details
PA5-53097
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
0.04-0.4 µg/mL | - |
Immunohistochemistry (IHC) |
1:200-1:500 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human ALOX15 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.1 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2637877 |
Product Specific Information
Immunogen sequence: RTVGEDPQGL FQKHREEELE ERRKLYRWGN WKDGLILNMA GAKLYDLPVD ERFLEDKRVD FEVSLAKGLA DLAIKDSLNV LTCWKDLDDF NRIFWCGQSK LAERVRDSWK EDALFGYQ
Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 66%.
Target Information
ALOX15 converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid. The protein also acts on C-12 of arachidonate as well as on linoleic acid.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 12-LOX; 12/15-lipoxygenase; 15-lipooxygenase-1; 15-LOX; 15-LOX2; Arachidonate 12-lipoxygenase, leukocyte-type; Arachidonate 15-lipoxygenase; Arachidonate omega-6 lipoxygenase; Hepoxilin A3 synthase Alox15; Linoleate 13S-lipoxygenase; Polyunsaturated fatty acid lipoxygenase ALOX15
Gene Aliases: 12-LOX; 15-LOX-1; 15LOX-1; ALOX15; LOG15
UniProt ID: (Human) P16050
Entrez Gene ID: (Human) 246
Molecular Function:
oxygenase
ossification
negative regulation of adaptive immune response
phosphatidylethanolamine biosynthetic process
leukotriene metabolic process
inflammatory response
positive regulation of cell-substrate adhesion
arachidonic acid metabolic process
lipoxygenase pathway
bone mineralization
positive regulation of actin filament polymerization
positive regulation of heterotypic cell-cell adhesion
response to endoplasmic reticulum stress
regulation of peroxisome proliferator activated receptor signaling pathway
cellular response to interleukin-13
wound healing
apoptotic cell clearance
hepoxilin biosynthetic process
oxidation-reduction process
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
regulation of engulfment of apoptotic cell
lipoxin A4 biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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