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Invitrogen
ALX1 Polyclonal Antibody
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FIGURE: 1 / 3
ALX1 Antibody (PA5150338) in IHC (P)
Immunohistochemistry analysis of ALX1 in paraffin-embedded human trachea tissue. Samples were incubated with ALX1 polyclonal antibody (Product # PA5150338) using a dilution of 1:500 for 1 hour at room temperature. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with ... View More
Product Details
PA5150338
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein within human Alx1 aa 1-326.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive control: MCF7 cell lysate, HepG2 cell lysate, Mouse articular cartilage tissue lysate, Rat brain tissue lysate, Rat embryo tissue lysate, human trachea tissue.
Subcellular location: Nucleus.
Target Information
Transcriptional activator that acts at a palindromic recognition sequence to enhance the activity of the SV40 and TK promoters. Functions as a repressor with the prolactin promoter in vivo. May play a role in chondrocyte differentiation and may also influence cervix development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ALX homeobox protein 1; CART-1; cartilage homeo protein 1; Cartilage homeoprotein 1; cartilage paired-class homeoprotein 1; epididymis luminal protein 23
Gene Aliases: AI314867; ALX1; C130005I02; CART1; CART1X; FND3; HEL23
UniProt ID: (Human) Q15699, (Rat) Q63087, (Mouse) Q8C8B0
Entrez Gene ID: (Human) 8092, (Rat) 25401, (Mouse) 216285
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
protein heterodimerization activity
protein homodimerization activity
homeodomain transcription factor
negative regulation of transcription from RNA polymerase II promoter
neural tube closure
regulation of transcription, DNA-templated
anterior/posterior pattern specification
positive regulation of epithelial to mesenchymal transition
mesenchymal cell development
embryonic limb morphogenesis
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
neuron development
embryonic skeletal system morphogenesis
stem cell development
palate development
skeletal system development
transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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