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Proteintech
AMH Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
14461-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AMH Fusion Protein Ag5670 (211-560 aa encoded by BC049194)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.41 mg/mL
Amount
61.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is specific to AMH.
Immunogen sequence: GLALTLQPR GEDSRLSTAR LQALLFGDDH RCFTRMTPAL LLLPRSEPAP LPAHGQLDTV PFPPPRPSAE LEESPPSADP FLETLTRLVR ALRVPPARAS APRLALDPDA LAGFPQGLVN LSDPAALERL LDGEEPLLLL LRPTAATTGD PAPLHDPTSA PWATALARRV AAELQAAAAE LRSLPGLPPA TAPLLARLLA LCPGGPGGLG DPLRALLLLK ALQGLRVEWR GRDPRGPGRA QRSAGATAAD GPCALRELSV DLRAERSVLI PETYQANNCQ GVCGWPQSDR NPRYGNHVVL LLKMQARGAA LARPPCCVPT AYAGKLLISL SEERISAHHV PNMVATECGC R (211-560 aa encoded by BC049194)
Target Information
Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140 kDa disulfide linked precursor that is cleaved to release the mature 30 kDa homodimer. Originally classified as a fetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: AMH; Anti - Mullerian hormone (Mulerian inhibiting substance); muellerian-inhibiting factor; muellerian-inhibiting substance; Mullerian inhibiting factor; Mullerian inhibiting substance
Gene Aliases: MIF; MIS
UniProt ID: (Human) P03971, (Rat) P49000, (Mouse) P27106
Entrez Gene ID: (Human) 268, (Rat) 25378, (Mouse) 11705
ovarian follicle development
preantral ovarian follicle growth
urogenital system development
Mullerian duct regression
sex determination
gonad development
response to xenobiotic stimulus
positive regulation of gene expression
Leydig cell differentiation
development of primary male sexual characteristics
positive regulation of SMAD protein import into nucleus
anti-Mullerian hormone signaling pathway
negative regulation of ovarian follicle development
cell-cell signaling
sex differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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