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Product Details
16664-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
AMZ2 Fusion Protein Ag10141 (1-360 aa encoded by BC056271)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MQIIRHSEQ TLKTALISKN PVLVSQYEKL DAGEQRLMNE AFQPASDLFG PITLHSPSDW ITSHPEAPQD FEQFFSDPYR KTPSPNKRSI YIQSIGSLGN TRIISEEYIK WLTGYCKAYF YGLRVKLLEP VPVSVTRCSF RVNENTHNLQ IHAGDILKFL KKKKPEDAFC VVGITMIDLY PRDSWNFVFG QASLTDGVGI FSFARYGSDF YSMHYKGKVK KLKKTSSSDY SIFDNYYIPE ITSVLLLRSC KTLTHEIGHI FGLRHCQWLA CLMQGSNHLE EADRRPLNLC PICLHKLQCA VGFSIVERYK ALVRWIDDES SDTPGATPEH SHEDNGNLPK PVEAFKEWKE WIIKCLAVLQ K (1-360 aa encoded by BC056271)
Target Information
AMZ2 (archaelysin family metallopeptidase 2), also known as archaemetzincin-2 or archeobacterial metalloproteinase-like protein 2, is a 360 amino acid protein belonging to the peptidase M54 family. Encoded by a gene that maps to human chromosome 17q24.2, AMZ2 is predominantly expressed in heart and testis. AMZ2 is also expressed in kidney, liver, pancreas, lung, brain and placenta, and in fetal tissues such as kidney, liver, lung and brain. AMZ2 participates in metal ion binding and functions as a zinc metalloprotease. AMZ2 is inhibited by both general metalloprotease inhibitors o-phenanthroline and batimastat. Exhibiting aminopeptidase activity, AMZ2 acts against Angiotensin in vitro, but does not hydrolyze either Neurogranin or Angiotensin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Archaemetzincin-2; archaemetzincins-2; archeobacterial metalloproteinase-like 2; Archeobacterial metalloproteinase-like protein 2
Gene Aliases: AA408420; AMZ2; BM-014; ESTM12; RGD1304846; X83328
UniProt ID: (Human) Q86W34, (Rat) Q400C7, (Mouse) Q400C8
Entrez Gene ID: (Human) 51321, (Rat) 360650, (Mouse) 13929
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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