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Invitrogen
ANGPTL4 Polyclonal Antibody
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FIGURE: 1 / 17
ANGPTL4 Antibody (40-9800) in IHC (P)
Immunohistochemistry analysis of ANGPTL4 showing staining in the cytoplasm and nucleus of paraffin-embedded mouse liver tissue (right) compared to a negative control without primary antibody (left). To expose target proteins, antigen retrieval was performed using 10mM sodium citrate (pH 6.0), microwaved for 8-15 min. Following antigen retrieval, tissues were blocked in 3% H2O2-methanol for 15 min at room te... View More
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.jpg?time=20220826?time=20220826 "ANGPTL4 Antibody (40-9800) in WB")
Product Details
40-9800
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
C. elegans,
Human,
Mouse,
Virus
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide derived from an internal region of the human ANGTPL4 protein, which differs from rat and mouse by one and two conservative amino acid replacements, respectively
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Angiopoietin-like protein 4 (ANGPTL4), is a secreted protein selectively expressed in adipose tissue, liver, and placenta1-3 that plays a variety of roles in vivo, ranging from adipogenesis to angiogenesis to carcinogenesis. The expression of ANGPTL4 is also under nutritional and hormonal control. ANGPTL4 has been observed to induce a strong pro-angiogenic response independent of vascular endothelial growth factor (VEGF), and its expression has been described in hypoxic human tissues as well as a variety of cancers, including liposarcoma, hepatocellular carcinoma, and conventional renal cell carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 425O18-1; angiopoietin-like 4; Angiopoietin-like protein 4; Angiopoietin-related protein 4; ANGPTL2; Fasting-i; Fasting-induced adipose factor; fibrinogen/angiopoietin-related protein; hepatic angiopoietin-related protein; Hepatic fibrinogen/angiopoietin-related protein; HFARP; major histocompatibility complex region NG27; peroxisome proliferator-activated receptor (PPAR) gamma induced angiopoietin-related protein; PPARG angiopoietin related protein; Secreted protein Bk89
Gene Aliases: ANGPTL4; ARP4; Bk89; Farp; FIAF; HARP; HFARP; Ng27; NL2; PGAR; Pgarg; PP1158; PSEC0166; TGQTL; UNQ171; UNQ171/PRO197
UniProt ID: (Human) Q9BY76, (Mouse) Q9Z1P8, (Rat) Q6TMA8
Entrez Gene ID: (Human) 51129, (Mouse) 57875, (Rat) 362850
angiogenesis
response to hypoxia
cell differentiation
negative regulation of apoptotic process
positive regulation of angiogenesis
negative regulation of lipoprotein lipase activity
protein homooligomerization
triglyceride homeostasis
negative regulation of endothelial cell apoptotic process
cellular response to starvation
positive regulation of lipid metabolic process
regulation of lipid metabolic process
negative regulation of catalytic activity
protein oligomerization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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