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ANGPTL4 Polyclonal Antibody
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FIGURE: 1 / 1
ANGPTL4 Antibody (600-401-R03) in WB
Western Blot analysis of ANGPTL4 using anti-ANGPTL4 antibody. Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel)/90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 30 µg of sample under reducing conditions. Lane 1: human hepatocellular carcinoma tumor tissue (HCCT) lysates, Lane 2: human HepG2 whole cell lysates, Lane 3: human U87 whole cell lysates. After electrophoresis, proteins were transferred to a nitrocellulose membrane at 150 mA for 50-90 minutes. Blocked the membrane with 5% no... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
600-401-R03
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ANGPTL4 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the C-terminal of human Angptl4.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Angiopoietin-like protein 4 (ANGPTL4), is a secreted protein selectively expressed in adipose tissue, liver, and placenta1-3 that plays a variety of roles in vivo, ranging from adipogenesis to angiogenesis to carcinogenesis. The expression of ANGPTL4 is also under nutritional and hormonal control. ANGPTL4 has been observed to induce a strong pro-angiogenic response independent of vascular endothelial growth factor (VEGF), and its expression has been described in hypoxic human tissues as well as a variety of cancers, including liposarcoma, hepatocellular carcinoma, and conventional renal cell carcinoma.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 425O18-1; Angiopoietin-like protein 4; Angiopoietin-related protein 4; ANGPTL2; Fasting-i; Fasting-induced adipose factor; fibrinogen/angiopoietin-related protein; Hepatic fibrinogen/angiopoietin-related protein; HFARP; major histocompatibility complex region NG27; Secreted protein Bk89
Gene Aliases: ANGPTL4; ARP4; Bk89; Farp; Fiaf; HFARP; Ng27; PGAR; Pgarg; PP1158; PSEC0166; UNQ171/PRO197
UniProt ID: (Mouse) Q9Z1P8, (Rat) Q6TMA8
Entrez Gene ID: (Mouse) 57875, (Rat) 362850
angiogenesis
cellular response to starvation
negative regulation of apoptotic process
positive regulation of lipid metabolic process
negative regulation of lipoprotein lipase activity
protein homooligomerization
triglyceride homeostasis
negative regulation of endothelial cell apoptotic process
response to hypoxia
regulation of lipid metabolic process
cell differentiation
negative regulation of catalytic activity
protein oligomerization
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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