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Abnova
ANXA4 Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 9
ANXA4 Antibody (H00000307-D01P) in WB
Western Blot analysis of ANXA4 expression in transfected 293T cell line (H00000307-T02) by ANXA4 MaxPab polyclonal antibody.
Lane 1: ANXA4 transfected lysate(36.10 KDa).
Lane 2: Non-transfected lysate.
Lane 1: ANXA4 transfected lysate(36.10 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00000307-D01P
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ANXA4 (NP_001144.1, 1 a.a. approximately 321 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MAMATKGGTV KAASGFNAME DAQTLRKAMK GLGTDEDAII SVLAYRNTAQ RQEIRTAYKS TIGRDLIDDL KSELSGNFEQ VIVGMMTPTV LYDVQELRRA MKGAGTDEGC LIEILASRTP EEIRRISQTY QQQYGRSLED DIRSDTSFMF QRVLVSLSAG GRDEGNYLDD ALVRQDAQDL YEAGEKKWGT DEVKFLTVLC SRNRNHLLHV FDEYKRISQK DIEQSIKSET SGSFEDALLA IVKCMRNKSA YFAEKLYKSM KGLGTDDNTL IRVMVSRAEI DMLDIRAHFK RLYGKSLYSF IKGDTSGDYR KVLLVLCGGD D
Target Information
Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 35-beta calcimedin; 36 kDa zymogen granule membrane-associated protein; Annexin A4; Annexin IV; annexin IV (placental anticoagulant protein II); Annexin-4; ANXA 4; ANXA4; Carbohydrate-binding protein p33/p41; Chromobindin-4; Endonexin I; epididymis secretory protein Li 274; Lipocortin IV; P32.5; PAP-II; Placental anticoagulant protein II; PP4-X; proliferation-inducing gene 28; proliferation-inducing protein 28; Protein II; unnamed protein product; ZAP 36/annexin IV; ZAP36
Gene Aliases: AI265406; AIV; ANX4; ANXA4; AW106930; HEL-S-274; P32.5; PAP-II; PIG28; PP4-X; Xanx-4; ZAP36
UniProt ID: (Human) P09525, (Mouse) P97429
Entrez Gene ID: (Human) 307, (Rat) 79124, (Mouse) 11746
negative regulation of transcription from RNA polymerase II promoter
signal transduction
Notch signaling pathway
negative regulation of tumor necrosis factor-mediated signaling pathway
epithelial cell differentiation
negative regulation of interleukin-8 production
negative regulation of apoptotic process
negative regulation of I-kappaB kinase/NF-kappaB signaling
regulation of transcription from RNA polymerase II promoter
exocytosis
negative regulation of NF-kappaB transcription factor activity
negative regulation of interleukin-8 secretion
kidney development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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