Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 5
APBB2 Antibody (PA5-101421) in IHC (P)
Immunohistochemistry analysis of APBB2 in human kidney cancer and adjacent normal tissues. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with APBB2 polyclonal antibody (Product # PA5-101421) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-101421
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human APBB2(Accession Q92870), corresponding to amino acid residues Q493-E543.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2850857
Product Specific Information
Antibody detects endogenous levels of total APBB2.
Target Information
The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta precursor protein and amyloid beta precursor-like protein 2. This protein contains two phosphotyrosine binding domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: amyloid beta (A4) precursor protein-binding, family B, member 2; amyloid beta A4 precursor protein-binding family B member 2; Amyloid beta precursor protein binding family B member 2; amyloid beta precursor protein-binding family B member 2; Amyloid-beta (A4) precursor protein-binding family B member 2; Fe65-like 1; Protein Fe65-like 1; zinc finger-like protein
Gene Aliases: 2310007D03Rik; APBB2; FE65L; FE65L1; RGD1562438; Rirl1; TR2L; Zfra
UniProt ID: (Human) Q92870, (Mouse) Q9DBR4
Entrez Gene ID: (Human) 323, (Rat) 305338, (Mouse) 11787
neuron migration
regulation of transcription, DNA-templated
cell cycle arrest
axon guidance
biological_process
extracellular matrix organization
negative regulation of cell growth
positive regulation of apoptotic process
negative regulation of apoptotic process
intracellular signal transduction
actin filament-based movement
protein stabilization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support