The synthetic peptide sequence is 101-120aa, ELQIARVEQATQAIPMERWC
Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
Amyloid-precursor-like protein 1 (APLP1) is a membrane-associated glycoprotein, whose gene is homologous to the APP gene, which has been shown to be involved in the pathogenesis of Alzheimer's disease. APLP1 is predominantly expressed in brain, particularly in the cerebral cortex postsynaptic density. The human gene has been mapped to chromosomal region 19q13.1. The gene is 11.8 kb long and contains 17 exons. APLP1 has been considered a candidate gene for CNF. All exon regions of the gene were amplified by the polymerase chain reaction and sequenced from DNA of CNF patients. No differences were observed between CNF patients and controls, suggesting that mutations in APLP1 are not involved in the etiology of CNF.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: amyloid beta (A4) precursor-like protein 1; amyloid precursor-like protein 1; Amyloid-like protein 1; APLP; APLP-1; APLP1; C30
Gene Aliases: APLP; APLP1; Aplp1_retired; RGD1561211