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Proteintech
APOA5 Polyclonal Antibody
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Product Details
18019-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Pig
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
APOA5 Fusion Protein Ag12568
Conjugate
Form
Liquid
Concentration
247 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
Apolipoprotein A4 (also known as ApoA-IV) is a plasma protein that is O-linked glycoprotein after proteolytic processing. ApoA4 is a major constituent of HDL and it also can be found on the surface of newly synthesized chylomicrons. The physiological function of ApoA4 is not completely identified so far, but several evidences from vitro studies indicate that this apolipoprotein involves in several steps of the reverse cholesterol transport pathway, which transports cholesterol from peripheral cells back to the liver.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apo-AV; apoA-V; Apolipoprotein A-V; apolipoprotein A-V precursor variant 3; Apolipoprotein A5; apolipoprotein AV; FLJ97995; MGC126836; MGC126838; Regeneration-associated protein 3
Gene Aliases: 1300007O05Rik; APOA5; APOAV; RAP3; UNQ411/PRO773
UniProt ID: (Human) Q6Q788, (Mouse) Q8C7G5
Entrez Gene ID: (Human) 116519, (Pig) 100286807, (Mouse) 66113
phospholipid binding
enzyme activator activity
heparin binding
lipid binding
cholesterol binding
cholesterol transporter activity
enzyme binding
phosphatidylcholine binding
lipase binding
low-density lipoprotein particle receptor binding
phosphatidylcholine-sterol O-acyltransferase activator activity
lipase activator activity
lipoprotein lipase activator activity
lipoprotein particle receptor binding
apolipoprotein
triglyceride metabolic process
cholesterol biosynthetic process
lipid transport
positive regulation of cholesterol esterification
positive regulation of triglyceride catabolic process
positive regulation of very-low-density lipoprotein particle remodeling
triglyceride catabolic process
regulation of intestinal cholesterol absorption
neuron projection regeneration
cholesterol efflux
phospholipid efflux
triglyceride-rich lipoprotein particle remodeling
high-density lipoprotein particle assembly
lipoprotein metabolic process
tissue regeneration
cholesterol homeostasis
reverse cholesterol transport
positive regulation of fatty acid biosynthetic process
phosphatidylcholine metabolic process
positive regulation of receptor-mediated endocytosis
positive regulation of lipid catabolic process
positive regulation of lipoprotein lipase activity
acylglycerol homeostasis
triglyceride homeostasis
transport
very-low-density lipoprotein particle remodeling
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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