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Invitrogen
APOBEC1 Polyclonal Antibody
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FIGURE: 1 / 4
APOBEC1 Antibody (PA5-11429) in IHC (P)
Immunohistochemistry analysis of APOBEC1 in formalin-fixed and paraffin-embedded human cancer tissue. Samples were incubated with APOBEC1 polyclonal antibody (Product # PA5-11429) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-11429
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of human Apobec1
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2.0 mg/mL
Amount
800 µg
Purification
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor and APOBEC1 stimulating protein . This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: apolipoprotein B editing complex 1; apolipoprotein B mRNA editing enzyme complex-1; apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1; apolipoprotein B mRNA-editing enzyme 1; mRNA(cytosine(6666)) deaminase 1; unnamed protein product
Gene Aliases: APO1; APOBEC-1; BEDP; CDAR1; HEPR
UniProt ID: (Human) P41238, (Mouse) P51908
Entrez Gene ID: (Human) 339, (Mouse) 11810
triglyceride metabolic process
response to xenobiotic stimulus
response to gamma radiation
cytidine to uridine editing
mRNA modification
low-density lipoprotein particle clearance
regulation of cell proliferation
lipoprotein metabolic process
lipoprotein biosynthetic process
lipoprotein transport
hypomethylation of CpG island
response to ethanol
mRNA stabilization
response to calcium ion
defense response to virus
DNA cytosine deamination
negative regulation of triglyceride metabolic process
positive regulation of mRNA modification
chromosomal 5-methylcytosine DNA demethylation pathway
regulation of mRNA metabolic process
negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
lipid metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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