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Invitrogen
APOBEC1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-19014
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (DVFYDPRELRKEAC) corresponding to the internal amino acids of APOBEC1 (aa 24-37).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with human based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor and APOBEC1 stimulating protein . This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: apolipoprotein B editing complex 1; mRNA(cytosine(6666)) deaminase 1; unnamed protein product
Gene Aliases: APOBEC-1; Cdar1
UniProt ID: (Mouse) P51908
Entrez Gene ID: (Mouse) 11810
triglyceride metabolic process
response to xenobiotic stimulus
response to gamma radiation
cytidine to uridine editing
mRNA modification
low-density lipoprotein particle clearance
regulation of cell proliferation
lipoprotein metabolic process
lipoprotein biosynthetic process
lipoprotein transport
hypomethylation of CpG island
response to ethanol
mRNA stabilization
response to calcium ion
defense response to virus
DNA cytosine deamination
negative regulation of triglyceride metabolic process
positive regulation of mRNA modification
chromosomal 5-methylcytosine DNA demethylation pathway
regulation of mRNA metabolic process
negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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