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APOC2 Polyclonal Antibody
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Product Details
BS-12497R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Apolipoprotein CII/APOC2, amino acids 31-101.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins. The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver where it is activated when monocytes differentiate into macrophages. The human apoC-II gene maps to chromosome 19q13.2 and encodes a 79 amino acid single chain protein that is a necessary cofactor for the activation of lipoprotein lipase, the enzyme that hydrolyzes triglycerides in plasma and transfers the fatty acids to tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: APC 2; APO C2; Apo CII; Apo-CII; APOC 2; ApoC II; apoC-II; APOC2 protein; ApoCII; Apolipoprotein C II; Apolipoprotein C-II; Apolipoprotein C2; Apolipoprotein CII; ApolipoproteinCII; MGC75082
Gene Aliases: APC2; APO-CII; APOC-II; APOC2
UniProt ID: (Human) P02655, (Mouse) Q05020
Entrez Gene ID: (Human) 344, (Mouse) 11813
lipid metabolic process
lipid transport
positive regulation of triglyceride catabolic process
positive regulation of very-low-density lipoprotein particle remodeling
negative regulation of very-low-density lipoprotein particle clearance
lipid catabolic process
negative regulation of cholesterol transport
cholesterol efflux
phospholipid efflux
triglyceride-rich lipoprotein particle remodeling
chylomicron remodeling
very-low-density lipoprotein particle remodeling
chylomicron remnant clearance
high-density lipoprotein particle clearance
lipoprotein catabolic process
cholesterol homeostasis
reverse cholesterol transport
positive regulation of fatty acid biosynthetic process
negative regulation of lipid metabolic process
negative regulation of receptor-mediated endocytosis
positive regulation of phospholipid catabolic process
triglyceride homeostasis
transport
positive regulation of phospholipase activity
lipoprotein transport
negative regulation of catalytic activity
positive regulation of lipoprotein lipase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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