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APOC2 Polyclonal Antibody
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APOC2 Antibody (PA5-102480) in IHC (P)
Immunohistochemistry analysis of APOC2 in mouse liver tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with APOC2 polyclonal antibody (Product # PA5-102480) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-102480
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human APOC2(Accession P02655), corresponding to amino acid residues G2-K52.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total APOC2.
Target Information
Apolipoproteins are protein components of plasma lipoproteins. The apolipoprotein C gene family encodes four homologous proteins designated apoC-I to -IV, which specifically modulate the metabolism of triglyceride-rich lipoproteins. The human apoC-I gene maps to chromosome 19q13.2 and is expressed primarily in the liver where it is activated when monocytes differentiate into macrophages. The human apoC-II gene maps to chromosome 19q13.2 and encodes a 79 amino acid single chain protein that is a necessary cofactor for the activation of lipoprotein lipase, the enzyme that hydrolyzes triglycerides in plasma and transfers the fatty acids to tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: APC 2; APO C2; Apo CII; APOC 2; ApoC II; APOC2 protein; ApoCII; Apolipoprotein C II; apolipoprotein C-II; Apolipoprotein CII; ApolipoproteinCII; MGC75082; unnamed protein product
Gene Aliases: APO-CII; APOC-II; RGD1560725
UniProt ID: (Human) P02655, (Mouse) Q05020, (Rat) G3V8D4
Entrez Gene ID: (Human) 344, (Mouse) 11813, (Rat) 292697
lipid metabolic process
lipid transport
positive regulation of triglyceride catabolic process
positive regulation of very-low-density lipoprotein particle remodeling
negative regulation of very-low-density lipoprotein particle clearance
negative regulation of cholesterol transport
cholesterol efflux
phospholipid efflux
chylomicron remodeling
chylomicron remnant clearance
high-density lipoprotein particle clearance
lipoprotein catabolic process
lipoprotein transport
positive regulation of fatty acid biosynthetic process
negative regulation of lipid metabolic process
negative regulation of receptor-mediated endocytosis
positive regulation of phospholipid catabolic process
triglyceride homeostasis
triglyceride-rich lipoprotein particle remodeling
very-low-density lipoprotein particle remodeling
cholesterol homeostasis
reverse cholesterol transport
response to xenobiotic stimulus
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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