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Invitrogen
APR3 Polyclonal Antibody
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FIGURE: 1 / 11
APR3 Antibody (PA5-100702) in ICC/IF
Immunocytochemistry analysis of APR3 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with APR3 polyclonal antibody (Product # PA5-100702) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG(H+L) (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG(H+L) (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-100702
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ATRAID(Accession Q6UW56), corresponding to amino acid residues L31-S81.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total APR3.
Target Information
Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3-Apr; All-trans retinoic acid-induced differentiation factor; apoptosis related protein 3; apoptosis related protein APR-3; Apoptosis-related protein 3; APR-3; H1E6 protein; p18; p18 protein
Gene Aliases: 0610007C21Rik; AI316792; APR--3; APR-3; APR3; ATRAID; C2orf28; HSPC013; p18; PRO240; RGD1311605; UNQ214/PRO240
UniProt ID: (Human) A8C1S2, (Mouse) Q6PGD0
Entrez Gene ID: (Human) 51374, (Rat) 298841, (Mouse) 381629
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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