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This gene encodes a protein that interacts with the conserved protein complex termed cohesin. The cohesin complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene.
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Protein Aliases: androgen induced inhibitor of proliferation; androgen-induced proliferation inhibitor; androgen-induced prostate proliferative shutoff associated protein; androgen-induced prostate proliferative shutoff associated protein AS3; androgen-induced prostate proliferative shutoff-associated protein AS3; androgen-induced shutoff 3; APRIN; Her-2 Tg; PDS5, regulator of cohesion maintenance, homolog B; proliferation inhibitor; unnamed protein product
Gene Aliases: APRIN; AS3; CG008; mKIAA0979; Tg(Wap-ERBB2)229Wzw; WAP-Her-2
UniProt ID: (Human) Q9NTI5, (Rat) Q6TRW4, (Mouse) Q4VA53
Entrez Gene ID: (Human) 23047, (Rat) 304218, (Mouse) 100710
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