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Proteintech
ARFIP2 Polyclonal Antibody
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Product Details
14548-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ARFIP2 Fusion Protein Ag6076 (138-341 aa encoded by BC000392)
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Amount
52.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: RKYESVLQL GRALTAHLYS LLQTQHALGD AFADLSQKSP ELQEEFGYNA ETQKLLCKNG ETLLGAVNFF VSSINTLVTK TMEDTLMTVK QYEAARLEYD AYRTDLEELS LGPRDAGTRG RLESAQATFQ AHRDKYEKLR GDVAIKLKFL EENKIKVMHK QLLLFHNAVS AYFAGNQKQL EQTLQQFNIK LRPPGAEKPS WLEEQ (138-341 aa encoded by BC000392)
Target Information
Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network. May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2 (PubMed:26507660). Participates also in autophagy by regulating the starvation-depdendent trafficking of ATG9A vesicles which deliver the PI4-kinase to the autophagosome initiation site (PubMed:31204568). In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG (PubMed:26296658). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ADP ribosylation factor interacting protein 2; ADP-ribosylation factor interacting protein 2 (arfaptin 2); ADP-ribosylation factor-interacting protein 2; Arfaptin 2; Arfaptin-2; Partner of RAC1; partner of RAC1 (arfaptin 2); POR1; unnamed protein product
Gene Aliases: 2310002N04Rik; ARFIP2; POR; POR1
UniProt ID: (Human) P53365, (Rat) Q6AY65, (Mouse) Q8K221
Entrez Gene ID: (Human) 23647, (Rat) 293344, (Mouse) 76932
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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