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Proteintech
ARHGDIB Polyclonal Antibody
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Product Details
16122-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ARHGDIB Fusion Protein Ag9078 (1-201 aa encoded by BC009200)
Conjugate
Form
Liquid
Concentration
0.14 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MTEKAPEPH VEEDDDDELD SKLNYKPPPQ KSLKELQEMD KDDESLIKYK KTLLGDGPVV TDPKAPNVVV TRLTLVCESA PGPITMDLTG DLEALKKETI VLKEGSEYRV KIHFKVNRDI VSGLKYVQHT YRTGVKVDKA TFMVGSYGPR PEEYEFLTPV EEAPKGMLAR GTYHNKSFFT DDDKQDHLSW EWNLSIKKEW TE (1-201 aa encoded by BC009200)
Target Information
Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: D4; d4 gdi; GDI LYGDI; Ly-GDI; Rho GDI 2; Rho GDP dissociation inhibitor (GDI) beta; Rho GDP-dissociation inhibitor 2; Rho-GDI beta
Gene Aliases: ARHGDIB; D4; GDIA2; GDID4; Ly-GDI; LYGDI; RAP1GN1; RhoGDI2
UniProt ID: (Human) P52566, (Mouse) Q61599
Entrez Gene ID: (Human) 397, (Rat) 362456, (Mouse) 11857
movement of cell or subcellular component
negative regulation of cell adhesion
multicellular organism development
regulation of Rho protein signal transduction
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction
cellular response to redox state
negative regulation of trophoblast cell migration
regulation of actin cytoskeleton reorganization
regulation of catalytic activity
metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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