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ARL2 Polyclonal Antibody

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ARL2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human ovary tumor using 10232-1-AP (ARL2 antibody) at dilution of 1:100 (under 25x lens).

ARL2 Antibody in Western Blot (WB) — Mouse spleen tissue were subjected to SDS PAGE followed by western blot with 10232-1-AP (ARL2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Product Details

10232-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2,000	View 4 publications 4 publications
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Immunocytochemistry (ICC/IF)	-	View 2 publications 2 publications

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human, Mouse, Rat
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	ARL2 Fusion Protein Ag0334 (2-184 aa encoded by BC002530) View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.2 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: GLLTILKKM KQKERELRLL MLGLDNAGKT TILKKFNGED IDTISPTLGF NIKTLEHRGF KLNIWDVGGQ KSLRSYWRNY FESTDGLIWV VDSADRQRMQ DCQRELQSLL VEERLAGATL LIFANKQDLP GALSSNAIRE VLELDSIRSH HWCIQGCSAV TGENLLPGID WLLDDISSRI FTAD (2-184 aa encoded by BC002530)

Target Information

This gene encodes a small GTP-binding protein of the RAS superfamily which functions as an ADP-ribosylation factor (ARF). The encoded protein is one of a functionally distinct group of ARF-like genes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

GTPase-activating protein Elmod2 is essential for meiotic progression in mouse oocytes.

Cell cycle (Georgetown, Tex.)

Zhou CX,Shi LY,Li RC,Liu YH,Xu BQ,Liu JW,Yuan B,Yang ZX,Ying XY,Zhang D

Wed May 03 00:00:00 EDT 2017

Effective protein inhibition in intact mouse oocytes through peptide nanoparticle-mediated antibody transfection.

PeerJ

Li R,Jin Z,Gao L,Liu P,Yang Z,Zhang D

Tue Apr 26 00:00:00 EDT 2016

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

The Journal of biological chemistry

Patil H,Saha A,Senda E,Cho KI,Haque M,Yu M,Qiu S,Yoon D,Hao Y,Peachey NS,Ferreira PA

Fri Oct 24 00:00:00 EDT 2014

MicroRNA-15b modulates cellular ATP levels and degenerates mitochondria via Arl2 in neonatal rat cardiac myocytes.

The Journal of biological chemistry

Nishi H,Ono K,Iwanaga Y,Horie T,Nagao K,Takemura G,Kinoshita M,Kuwabara Y,Mori RT,Hasegawa K,Kita T,Kimura T

Fri Feb 12 00:00:00 EST 2010

Truncation mutation in HRG4 (UNC119) leads to mitochondrial ANT-1-mediated photoreceptor synaptic and retinal degeneration by apoptosis.

Investigative ophthalmology & visual science

Mori N,Ishiba Y,Kubota S,Kobayashi A,Higashide T,McLaren MJ,Inana G

Sat Apr 01 00:00:00 EST 2006

Truncation mutation in HRG4 (UNC119) leads to mitochondrial ANT-1-mediated photoreceptor synaptic and retinal degeneration by apoptosis.

Investigative ophthalmology & visual science

Mori N,Ishiba Y,Kubota S,Kobayashi A,Higashide T,McLaren MJ,Inana G

Sat Apr 01 00:00:00 EST 2006

Bioinformatics

Protein Aliases: ADP-ribosylation factor like GTPase 2; ADP-ribosylation factor-like 2; ADP-ribosylation factor-like protein 2; ADP-ribosylation-like 2; arf-like protein 2

Gene Aliases: 2610009M23Rik; AI115441; ARFL2; Arl184; ARL2; AW553335

UniProt ID: (Human) P36404, (Mouse) Q9D0J4, (Rat) O08697

Entrez Gene ID: (Human) 402, (Mouse) 56327, (Rat) 65142

Function(s)

cell cycle small GTPase mediated signal transduction acetylcholine transport regulation of microtubule polymerization positive regulation of microtubule polymerization negative regulation of GTPase activity centrosome organization maintenance of protein location in nucleus tubulin complex assembly positive regulation of cell-substrate adhesion regulation of insulin secretion bicellular tight junction assembly metabolic process

Process(es)

GTPase activity GTPase inhibitor activity protein binding GTP binding nucleotide binding GDP binding

ARL2 Polyclonal Antibody

Product Details

10232-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Product Specific Information

Target Information

Bioinformatics

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