Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
ARPC4 Fusion Protein Ag1366 (1-168 aa encoded by BC012596) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.38 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: TATLRPYLS AVRATLQAAL CLENFSSQVV ERHNKPEVEV RSSKELLLQP VTISRNEKEK VLIEGSINSV RVSIAVKQAD EIEKILCHKF MRFTMMRAEN FFILRRKPVE GYDISFLITN FHTEQMYKHK LVDFVIHFME EIDKEISEMK LSVNARARIV AEEFLKNF (1-168 aa encoded by BC012596)
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3, which results in the production of a fusion protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: actin related protein 2/3 complex subunit 4, 20kDa; actin related protein 2/3 complex, subunit 4, 20kDa; Actin-related protein 2/3 complex subunit 4; Arp2/3 complex 20 kDa subunit; arp2/3 protein complex subunit p20; MGC13544; p20-ARC
Gene Aliases: 20kDa; 5330419I20Rik; AI327076; ARC20; ARPC4; P20-ARC
UniProt ID: (Human) P59998, (Mouse) P59999
Entrez Gene ID: (Human) 10093, (Mouse) 68089, (Rat) 297518
Molecular Function:
actin or actin-binding cytoskeletal protein
cytoskeletal protein
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